ImmunoCellular Therapeutics (MKT:IMUC) announced Monday that it was featured on CNN’s Sanjay Gupta MD last weekend.
The show profiled the biotech company’s brain tumour vaccine ICT-107,
which is in Phase 2b clinical trials to treat patients with
glioblastoma multiforme, an aggressive brain cancer.
Phase 2 trial is a double-blind and placebo-controlled study aimed to
evaluate the safety and efficacy of the vaccine.
The study is
enrolling patients at medical institutions in collaboration with leading
experts and opinion leaders in neuro-oncology.
Sanjay Gupta, a
practicing neurosurgeon, reports on health and medical news for Starting
Point with Soledad O’Brien, Anderson Cooper 360 and anchors the weekend
medical affairs program during the weekends.
A transcript of the CNN show can be accessed, by clicking this link: http://edition.cnn.com/TRANSCRIPTS/1208/11/hcsg.01.html
late July, the biotech company said the U.S. Food and Drug
Administration gave clearance to start Phase I clinical trials of
ICT-121, a vaccine that targets an antigen expressed in tumours.
trial, which will be performed at a Los Angeles-based medical centre,
will test the vaccine on 20 patients with glioblastoma multiforme, an
aggressive brain cancer.
Like ICT-107, now in Phase II trials
treating subjects with the same type of brain cancer, the ICT-121
treatment is the second dendritic cell-based vaccine to enter the
Both brain tumour vaccines work by turning a patient’s immune system against tumour associated antigens. This is done by
out dendritic cells and loading them with antigens. The cells, then,
are reinserted into the patient’s body to trigger an immune response.
company seeks to develop and sell new therapeutics using the immune
system to fight cancer. ImmunoCellular is based in Los Angeles.